{"id":6731,"date":"2026-04-12T11:09:13","date_gmt":"2026-04-12T11:09:13","guid":{"rendered":"https:\/\/novumlab.eu\/product\/foxo4-dri\/"},"modified":"2026-04-12T11:09:13","modified_gmt":"2026-04-12T11:09:13","slug":"foxo4-dri","status":"publish","type":"product","link":"https:\/\/novumlab.eu\/de\/produkt\/foxo4-dri\/","title":{"rendered":"FOXO4-DRI"},"content":{"rendered":"

FOXO4-DRI \u2013 Senolytisches Forschungspeptid<\/strong><\/h3>\n

FOXO4-DRI ist ein D-Retro-Inverso-Peptid, das entwickelt wurde, um die FOXO4-p53-Interaktion in seneszenten Zellen zu st\u00f6ren. Es wurde erstmals von Baar et al. (2017) in der Fachzeitschrift Cell beschrieben und stellt einen neuartigen Ansatz in der Seneszenzforschung dar.<\/p>\n

\n

Forschungshintergrund:<\/strong><\/h3>\n

FOXO4-DRI wurde in der pr\u00e4klinischen Seneszenzforschung untersucht. Das Peptid ist als zellpenetrierende Verbindung konzipiert, die den FOXO4-p53-Komplex st\u00f6rt, der als \u00dcberlebensmechanismus in seneszenten Zellen identifiziert wurde.<\/p>\n

In ver\u00f6ffentlichten Studien wurde FOXO4-DRI an gealterten Tiermodellen untersucht, wobei seine Auswirkungen auf Marker der zellul\u00e4ren Seneszenz untersucht wurden. Die D-Retro-Inverso-Konfiguration bietet im Vergleich zu Peptiden in L-Form eine erh\u00f6hte Protease-Resistenz.<\/p>\n

\n

Informationen zur Verbindung:<\/strong><\/h3>\n
    \n
  • Klassifizierung:<\/strong> Synthetisches, zellpenetrierendes senolytisches Forschungspeptid<\/li>\n<\/ul>\n
    \n

    Produktspezifikationen:<\/strong><\/h3>\n
      \n
    • Form:<\/strong> Lyophilisiertes (gefriergetrocknetes) Pulver<\/li>\n
    • Reinheit:<\/strong> \u226598 % (HPLC-verifiziert)<\/li>\n
    • Beh\u00e4lter:<\/strong> Borosilikatglasfl\u00e4schchen Typ I<\/li>\n
    • Lagerung:<\/strong> -20 \u00b0C empfohlen, 2\u20138 \u00b0C f\u00fcr kurze Zeit<\/li>\n
    • Rekonstitution:<\/strong> Bakteriostatisches Wasser oder steriles Wasser<\/li>\n
    • Hersteller:<\/strong> NovumLab<\/li>\n
    • Qualit\u00e4tskontrolle:<\/strong> Jede Charge wird unabh\u00e4ngig gepr\u00fcft<\/li>\n
    • Verwendungszweck:<\/strong> Ausschlie\u00dflich f\u00fcr<\/strong> die In-vitro-Laborforschung<\/li>\n<\/ul>\n
      \n

      Dieses Produkt ist kein Arzneimittel, Lebensmittel oder Kosmetikum und sollte unter Laborbedingungen von qualifiziertem Fachpersonal gehandhabt werden. Alle Produktinformationen dienen ausschlie\u00dflich zu Bildungszwecken. Das Produkt ist kein Lebensmittel oder Nahrungserg\u00e4nzungsmittel und nicht f\u00fcr den menschlichen Verzehr geeignet. Nur f\u00fcr die In-vitro-Forschung bestimmt.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

      FOXO4-DRI ist ein zelldurchdringendes Peptid, das in der Seneszenzforschung untersucht wird. Es wurde auf seine Interaktion mit der FOXO4\/p53-Signalachse untersucht. Lyophilisiertes Pulver. Reinheit \u226598% (HPLC). Nur f\u00fcr die In-vitro-Forschung geeignet.<\/p>\n","protected":false},"featured_media":2872,"comment_status":"open","ping_status":"closed","template":"","meta":{"_themeisle_gutenberg_block_has_review":false},"product_brand":[],"product_cat":[2085],"product_tag":[1411,2105,2135,2134,1412],"class_list":{"0":"post-6731","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-langlebigkeit-wohlbefinden","7":"product_tag-foxo4-dri","8":"product_tag-longevity-research","9":"product_tag-p53-research","10":"product_tag-senescence-research","11":"product_tag-senolytisches-peptid","13":"first","14":"outofstock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"supplier_id":null,"supplier_sku":"","barcode":null,"atum_controlled":true,"out_stock_date":"2026-04-12 11:09:20","out_stock_threshold":null,"inheritable":false,"inbound_stock":null,"stock_on_hold":0,"sold_today":0,"sales_last_days":0,"reserved_stock":null,"customer_returns":null,"warehouse_damage":null,"lost_in_post":null,"other_logs":null,"out_stock_days":23,"lost_sales":0,"has_location":null,"update_date":"2026-05-06T00:40:56","atum_locations":[],"atum_stock_status":"outofstock","restock_status":false,"low_stock_amount":"","sales_update_date":"2026-05-06T00:40:56","calc_backorders":null,"yoast_head":"\nFOXO4-DRI - NovumLab.eu<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/novumlab.eu\/de\/produkt\/foxo4-dri\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FOXO4-DRI - NovumLab.eu\" \/>\n<meta property=\"og:description\" content=\"FOXO4-DRI ist ein zelldurchdringendes Peptid, das in der Seneszenzforschung untersucht wird. 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